Tool

Glycan Array QSAR Tool (v1.0.3)
A quantitative structure-activity relationship (QSAR) study on glycan array data to determine the specificities of glycan-binding proteins

The Glycan Array QSAR Tool provides a novel quantitative structure-activity relationship (QSAR) method to analyze the glycan array data. It first decomposes glycan chains into mono-, di-, tri-, or tetra-saccharide sub-trees. The bond information is also incorporated into the sub-trees to help distinguish the glycan chains structurally. Then, the tool perform partial least squares (PLS) regression on glycan array data using the sub-trees as features. Based on the regression coefficients of PLS, the tool will report the sub-trees that determine the binding specificities of glycan-binding proteins